What is randomization?

Randomization is a process used in some clinical trials to prevent bias, which can arise when human choices or other unrelated factors affect the trial’s results. This process helps ensure that unknown factors do not influence the outcomes. If you participate in a trial using randomization, the assignment to either an investigational group (which receives the new treatment being tested) or a control group (which receives the most widely accepted treatment for cancer) occurs by chance. Neither you nor your doctor gets to choose your group.

National Cancer Institute(NCI)

Your assignment is determined with a computer program or table of random numbers.

• If you are assigned to the control group, you will receive the standard treatment for your cancer.
• If you are assigned to the treatment group, you will get the new treatment being tested.

Comparing these groups often clearly shows which treatment is more effective or has fewer side effects. If you are considering joining a randomized clinical trial, you should understand that you have an equal chance of being assigned to either group.

Visit the National Cancer Institute to learn more about randomization.